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Aeromexico, a low-cost Mexican airline, via Skyscanner have round trip airfares travelling from San Francisco (SFO) to Santiago Chile (SCL) for $ 634-$ 688, making 1 stop in Mexico City. These are basic economy fares so review fare restrictions before purchasing.

Travel Availability:

Departs SFO: Oct 26-31; Nov 4 – Dec 10
Returns: wide and good availability returns

To book this deal, enter travel information on Skyscanner [skyscanner.com], who will find the lowest possible prices for you. Then select a known and reputable OTA to complete your booking!